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Dan Gibson Selected Research

Prodrugs

1/2021Platinum(IV) anticancer agents; are we en route to the holy grail or to a dead end?
11/2020Platinum(IV)-Estramustine Multiaction Prodrugs Are Effective Antiproliferative Agents against Prostate Cancer Cells.
4/2020Multiaction Pt(IV) Carbamate Complexes Can Codeliver Pt(II) Drugs and Amine Containing Bioactive Molecules.
1/2020A Multi-action and Multi-target RuII -PtIV Conjugate Combining Cancer-Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers.
11/2019Dual-Targeting Dual-Action Platinum(IV) Platform for Enhanced Anticancer Activity and Reduced Nephrotoxicity.
4/2019An Anticancer PtIV Prodrug That Acts by Mechanisms Involving DNA Damage and Different Epigenetic Effects.
1/2019Multi-action Pt(IV) anticancer agents; do we understand how they work?
5/2018Triple action Pt(iv) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance.
11/2017A Quadruple-Action Platinum(IV) Prodrug with Anticancer Activity Against KRAS Mutated Cancer Cell Lines.
1/2017Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates.
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Dan Gibson Research Topics

Disease

38Neoplasms (Cancer)
04/2022 - 11/2002
5Ovarian Neoplasms (Ovarian Cancer)
06/2015 - 11/2002
2Colorectal Neoplasms (Colorectal Cancer)
11/2017 - 03/2016
2Colonic Neoplasms (Colon Cancer)
11/2017 - 07/2006
1Carcinoma (Carcinomatosis)
04/2022
1Stroke (Strokes)
01/2022
1Body Weight (Weight, Body)
12/2021
1Lewis Lung Carcinoma
12/2021
1Prostatic Neoplasms (Prostate Cancer)
11/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
05/2018
1Adenocarcinoma of Lung
11/2017
1Adenocarcinoma
11/2017
1Mitochondrial Diseases (Mitochondrial Disease)
03/2016
1Inflammation (Inflammations)
10/2014
1Lung Neoplasms (Lung Cancer)
10/2014

Drug/Important Bio-Agent (IBA)

22Cisplatin (Platino)FDA LinkGeneric
12/2021 - 11/2002
17LigandsIBA
04/2022 - 11/2002
17PlatinumIBA
04/2022 - 07/2004
14ProdrugsIBA
01/2021 - 02/2015
9DNA (Deoxyribonucleic Acid)IBA
04/2022 - 11/2002
6transplatinIBA
06/2020 - 11/2002
5Pharmaceutical PreparationsIBA
01/2020 - 07/2004
3Biological ProductsIBA
04/2019 - 03/2016
3Cytotoxins (Cytolysins)IBA
01/2017 - 06/2007
3PiperazineIBA
06/2007 - 11/2002
2Valproic Acid (Depakote)FDA LinkGeneric
05/2018 - 06/2015
2Oxaliplatin (Eloxatin)FDA LinkGeneric
03/2016 - 11/2014
2methylamine (methylammonium)IBA
09/2013 - 07/2006
2CyclohexylaminesIBA
11/2010 - 07/2006
2Cell ExtractsIBA
07/2009 - 03/2009
22-propylamine (isopropylamine)IBA
07/2006 - 11/2002
2n-butylamineIBA
07/2006 - 11/2002
2PicolinesIBA
11/2003 - 11/2002
2piperidineIBA
11/2003 - 11/2002
1kojic acidIBA
04/2022
1AluminumIBA
04/2022
1IronIBA
04/2022
1EstramustineFDA Link
11/2020
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2020
1Acetates (Acetic Acid Esters)FDA Link
12/2019
1ChloridesIBA
12/2019
1satraplatin (JM 216)IBA
12/2019
1Liposomes (Liposome)IBA
11/2019
1octanoic acid (caprylic acid)IBA
04/2019
1Cytostatic AgentsIBA
01/2019
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
05/2018
1Ibuprofen (Motrin)FDA LinkGeneric
05/2018
1ras ProteinsIBA
11/2017
1Glucose (Dextrose)FDA LinkGeneric
03/2016
1Fluorouracil (Carac)FDA LinkGeneric
03/2016
1CaspasesIBA
03/2016
1Antineoplastic Agents (Antineoplastics)IBA
02/2015
1Histone Deacetylases (Histone Deacetylase)IBA
11/2014
1CytokinesIBA
10/2014
1amminedichloro(cyclohexylamine)platinum(II)IBA
11/2010
1AminesIBA
03/2009
14-(1-piperidino)piperidineIBA
07/2006
1dimethylamine (dimethylamine nitrate)IBA
07/2006
1quinone (benzoquinone)IBA
07/2004
1High Mobility Group ProteinsIBA
11/2003
1Carboplatin (JM8)FDA LinkGeneric
05/2003
1calf thymus DNAIBA
11/2002
1DNA AdductsIBA
11/2002

Therapy/Procedure

3Therapeutics
04/2022 - 10/2014
2Drug Therapy (Chemotherapy)
01/2020 - 10/2014
1Thrombectomy
01/2022
1Photochemotherapy (Photodynamic Therapy)
01/2020